Picking up from where the last game left off, Syphon Filter 2 starts with Lian Xing being infected with the Syphon Filter virus. Gabe Logan must find the antidote, stop the spread of the virus, and clear his name. To do all of this, Gabe will have to travel the world and face many enemies. Just like the first game, he can take out foes with quick shots to the head.

But this time around, Gabe can also sneak up behind someone and slash his throat. Gabe also has help with his mission, as the player will be able to take the role of Lian in several levels. If you get tired of fighting computer drones, a new Deathmatch mode lets you battle your friends. Remember, stealth will keep you alive longer than brute force in Syphon Filter 2.